Microscopic cell changes during optic nerve swelling

OPTIC NEURITIS

Vision depends upon more than the ability of the eyes to capture light. Once visual information has been detected by the retina, it must be transmitted efficiently to the brain for interpretation. This communication occurs via the optic nerve, a highly specialised structure containing more than one million nerve fibres that connect each eye to the visual centres of the brain. Damage to the optic nerve can impair this transfer of information, resulting in visual dysfunction even when the eye itself appears otherwise healthy. Conditions affecting the optic nerve are collectively referred to as optic neuropathies(1).

Optic neuropathy is not a single disease, but rather a term used to describe damage or dysfunction of the optic nerve arising from a variety of causes. Depending upon the underlying condition, optic nerve damage may occur gradually over many years or develop relatively suddenly. Because the optic nerve is responsible for transmitting all visual information from the eye to the brain, injury to this structure has the potential to significantly affect visual performance, colour perception, visual fields and overall quality of vision(2).